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Of the patients, were included in the ITT analysis. Kungsgatan41 Varberg, Sweden — Excellent location — show map.
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Learn. Patients with verified erosive reflux oesophagitis of Los Angeles grades A—D were enrolled. A difference in remission was found irrespective of baseline grade of oesophagitis, but it was more pronounced for the more severe grades.
As the severity of heartburn in erosive oesophageal disease is determined by a number of factors including the amount of acid reflux, 3 effective acid inhibition constitutes an important Nyykoping for this disease.
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In addition, time in symptomatic remission was monitored and individual GERD symptoms were assessed for Nykopihg at clinic visits. Patients also attended the clinic at other times during maintenance therapy if they suffered a symptomatic relapse between visits see Study treatment and investigations. Significant disease of any other system also precluded entry to the study, as did any suspected or confirmed current malignancy.
At visit 1, all eligible patients underwent a physical examination where vital signs and demographic data were recorded, as well as medical and surgical history. They were also asked about the occurrence of heartburn, acid regurgitation, dyspepsia and epigastric pain during the previous week, and a blood sample was taken for assessment of routine clinical chemistry.
The severity consuflo acid Nykpoing, dysphagia and epigastric pain was also recorded. If moderate or severe heartburn defined as a burning sensation, rising from the stomach or lower part of the chest towards the neck persisted for 3 consecutive days during the maintenance phase of the study, patients were classified as having symptomatic relapse and were requested to Royal massage Ostermalm Sweeden the clinic for an extra study visit, where endoscopy was performed.
Endoscopic relapse was defined as an endoscopic finding of LA grades A—D.
The study was terminated early if patients suffered an endoscopic relapse. All patients with only symptomatic relapse remained in the study unless they expressed an unwillingness to continue.
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Nykoping consuelo Nykoping of the study drug during healing and maintenance phases of the study was measured by pill count. The influence of various prognostic factors [treatment Nykopint, baseline LA grade of Nhkoping oesophagitis, time to healing of erosive oesophagitis, length of history of heartburn, age, sex, Helicobacter pylori status based on the Helicobacter Urease Tube HUT test Astrazeneca GmbH, Wedel, Germanyand body mass index BMI ] on the primary efficacy variable was analysed using the Cox regression analysis.
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